Ralph J Bernacki: search on Z-Library

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1

Syntheses and structure–activity relationships of novel 3′-difluoromethyl and 3′-trifluoromethyl-taxoids

Larissa V. Kuznetsova, Antonella Pepe, Ioana M. Ungureanu, Paula Pera, Ralph J. Bernacki, Iwao Ojima

Journal:

Journal of Fluorine Chemistry

Year:

2008

Language:

english

File:

PDF, 896 KB

english, 2008

2

Synthesis and biological evaluation of novel 3′-difluorovinyl taxoids

Larissa Kuznetsova, Liang Sun, Jin Chen, Xianrui Zhao, Joshua Seitz, Manisha Das, Yuan Li, Jean M. Veith, Paula Pera, Ralph J. Bernacki, Shujun Xia, Susan B. Horwitz, Iwao Ojima

Journal:

Journal of Fluorine Chemistry

Year:

2012

Language:

english

File:

PDF, 1.25 MB

english, 2012

3

Effects of a membrane sugar analogue, 6-deoxy-6-fluoro-d-galactose, on the L1210 leukemic cell ectosialyltransferase system

Michael J. Morin, Carl W. Porter, Charles R. Petrie III, Walter Korytnyk, Ralph J. Bernacki

Journal:

Biochemical Pharmacology

Year:

1983

Language:

english

File:

PDF, 1.08 MB

english, 1983

4

Syntheses and Structure−Activity Relationships of Novel Nor-seco Taxoids

Ojima, Iwao, Lin, Songnian, Chakravarty, Subrata, Fenoglio, Ivana, Park, Young Hoon, Sun, Chung-Ming, Appendino, Giovanni, Pera, Paula, Veith, Jean M., Bernacki, Ralph J.

Journal:

Journal of Organic Chemistry

Year:

1998

Language:

english

File:

PDF, 216 KB

english, 1998

5

Targeting 5'-deoxy-5'-(methylthio)adenosine phosphorylase by 5'-haloalkyl analogs of 5'-deoxy-5'-(methylthio)adenosine

Sufrin, Janice R., Spiess, Arthur J., Kramer, Debora L., Libby, Paul R., Miller, John T., Bernacki, Ralph J., Lee, Younha, Borchardt, Ronald T., Porter, Carl W.

Journal:

Journal of Medicinal Chemistry

Year:

1991

Language:

english

File:

PDF, 906 KB

english, 1991

6

Analogs of cell surface carbohydrates. Synthesis of d-galactose derivatives having an ethynyl, vinyl or epoxy residue at C-5

Ho H. Lee, Philip G. Hodgson, Ralph J. Bernacki, Walter Korytnyk, Moheswar Sharma

Journal:

Carbohydrate Research

Year:

1988

Language:

english

File:

PDF, 1.00 MB

english, 1988

7

Partial Circumvention of P-Glycoprotein-Mediated Multidrug Resistance by Doxorubicin-14-O-Hemiadipate

Olga V. Leontieva, Maria N. Preobrazhenskaya, Ralph J. Bernacki

Journal:

Investigational New Drugs

Year:

2002

Language:

english

File:

PDF, 1.30 MB

english, 2002

8

Syntheses and evaluation of novel fatty acid-second-generation taxoid conjugates as promising anticancer agents

Larissa Kuznetsova, Jin Chen, Liang Sun, Xinyuan Wu, Antonella Pepe, Jean M. Veith, Paula Pera, Ralph J. Bernacki, Iwao Ojima

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 127 KB

english, 2006

9

The biochemical and ultrastructural effects of tunicamycin and D-glucosamine in L1210 leukemic cells

Michael J. Morin, Carl W. Porter, Patricia McKernan, Ralph J. Bernacki

Journal:

Journal of Cellular Physiology

Year:

1983

Language:

english

File:

PDF, 946 KB

english, 1983

10

Regulation of Rat-Liver Glycoprotein: N-Acetylneuraminic Acid Transferase Activity by Pyrimidine Nucleotides

Ralph J. BERNACKI

Journal:

Year:

1975

Language:

english

File:

PDF, 472 KB

english, 1975

11

Design, Synthesis, and Biological Evaluation of Novel C14−C3′BzN-Linked Macrocyclic Taxoids †

Sun, Liang, Geng, Xudong, Geney, Raphaël, Li, Yuan, Simmerling, Carlos, Li, Zhong, Lauher, Joseph W., Xia, Shujun, Horwitz, Susan B., Veith, Jean M., Pera, Paula, Bernacki, Ralph J., Ojima, Iwao

Journal:

Journal of Organic Chemistry

Year:

2008

Language:

english

File:

PDF, 1.66 MB

english, 2008

12

Activity of paclitaxel liposome formulations against human ovarian tumor xenografts

Amarnath Sharma, Eric Mayhew, Lois Bolcsak, C. Cavanaugh, P. Harmon, Andrew Janoff, Ralph J. Bernacki

Journal:

International Journal of Cancer

Year:

1997

Language:

english

File:

PDF, 84 KB

english, 1997

13

Use of the Tubulin Bound Paclitaxel Conformation for Structure-Based Rational Drug Design

Raphaël Geney, Liang Sun, Paula Pera, Ralph J. Bernacki, Shujun Xia, Susan B. Horwitz, Carlos L. Simmerling, Iwao Ojima

Journal:

Chemistry & Biology

Year:

2005

Language:

english

File:

PDF, 513 KB

english, 2005

14

In Vitro Antitumor Activity of 9-Nitro-Camptothecin as a Single Agent and in Combination with other Antitumor Drugs

RALPH J. BERNACKI, PAULA PERA, PETER GAMBACORTA, YSEULT BRUN, WILLIAM R. GRECO

Journal:

Annals of the New York Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 2.13 MB

english, 2000

15

ChemInform Abstract: Design, Synthesis and Biological Activity of Novel C2—C3′ N-Linked Macrocyclic Taxoids.

Iwao Ojima, Xudong Geng, Songnian Lin, Paula Pera, Ralph J. Bernacki

Journal:

Year:

2002

File:

PDF, 36 KB

2002

16

Synthesis and Biological Effects of 5′-Deoxy-5′-(Cyclo-Propylmethylthio)Adenosine

Sufrin, Janice R., Spiess, Arthur J., Karny, John F., Kramer, Debora L., Hughes, Robert G., Bernacki, Ralph J., Porter, Carl W.

Journal:

Nucleosides and Nucleotides

Year:

1989

Language:

english

File:

PDF, 397 KB

english, 1989

17

The Use of a Novel Taxane-Based P-Glycoprotein Inhibitor to Identify Mutations That Alter the Interaction of the Protein with Paclitaxel

Gruol, Donald J., Bernd, Josh, Phippard, Alba E., Ojima, Iwao, Bernacki, Ralph J.

Journal:

Molecular Pharmacology

Year:

2001

File:

PDF, 187 KB

2001

18

Versatile intermediates in the selective modification of the amino function of 2-amino-2-deoxy-d-mannopyranose and the 3-position of 2-acetamido-2-deoxy-d-mannose: Potential membrane modifiers in neoplastic control

Norman J. Angelino, Ralph J. Bernacki, Moheswar Sharma, Onda Dodson-Simmons, Walter Korytnyk

Journal:

Carbohydrate Research

Year:

1995

Language:

english

File:

PDF, 1004 KB

english, 1995

19

Ultrastructural evidence for ectoglycosyltransferase systems

PORTER, CARL W., BERNACKI, RALPH J.

Journal:

Year:

1975

File:

PDF, 696 KB

1975

20

Role of galaptin in ovarian carcinoma adhesion to extracellular matrix in vitro

Howard J. Allen, Daniel Sucato, Barbara Woynarowska, Sally Gottstine, Ashu Sharma, Ralph J. Bernacki

Journal:

Journal of Cellular Biochemistry

Year:

1990

Language:

english

File:

PDF, 1.16 MB

english, 1990

21

Interactions of human ovarian tumor cells with human mesothelial cells grown on extracellular matrix: An in vitro model system for studying tumor cell adhesion and invasion

Michael J. Niedbala, Kent Crickard, Ralph J. Bernacki

Journal:

Experimental Cell Research

Year:

1985

Language:

english

File:

PDF, 8.87 MB

english, 1985

22

Structure-Activity Relationships of New Taxoids Derived from 14.beta.-Hydroxy-10-deacetylbaccatin III

Ojima, Iwao, Park, Young Hoon, Sun, Chung-Ming, Fenoglio, Ivana, Appendino, Giovanni, Pera, Paula, Bernacki, Ralph J.

Journal:

Journal of Medicinal Chemistry

Year:

1994

Language:

english

File:

PDF, 703 KB

english, 1994

23

Synthesis and biological activity of 3′-alkyl- and 3′-alkenyl-3′-dephenyldocetaxels

Iwao Ojima, Olivier Duclos, Scott D. Kuduk, Chung-Ming Sun, John C. Slater, François Lavelle, Jean M. Veith, Ralph J. Bernacki

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 320 KB

english, 1994

24

Syntheses and Structure−Activity Relationships of Taxoids Derived from 14β-Hydroxy-10-deacetylbaccatin III

Ojima, Iwao, Slater, John C., Kuduk, Scott D., Takeuchi, Craig S., Gimi, Rayomand H., Sun, Chung-Ming, Park, Young Hoon, Pera, Paula, Veith, Jean M., Bernacki, Ralph J.

Journal:

Journal of Medicinal Chemistry

Year:

1997

Language:

english

File:

PDF, 390 KB

english, 1997

25

Structure−Activity Relationships of Ring C-Secotaxoids. 1. Acylative Modifications †

Appendino, Giovanni, Bettoni, Piergiorgio, Noncovich, Alain, Sterner, Olov, Fontana, Gabriele, Bombardelli, Ezio, Pera, Paula, Bernacki, Ralph J.

Journal:

Journal of Natural Products

Year:

2004

Language:

english

File:

PDF, 81 KB

english, 2004

26

New taxanes as highly efficient reversal agents for multi-drug resistance in cancer cells

Iwao Ojima, Pierre-Yves Bounaud, Craig Takeuchi, Paula Pera, Ralph J. Bernacki

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 430 KB

english, 1998

27

Glycosidases in cancer and invasion

Ralph J. Bernacki, Michael J. Niedbala, Walter Korytnyk

Journal:

Cancer and Metastasis Reviews

Year:

1985

Language:

english

File:

PDF, 2.96 MB

english, 1985

28

Synthesis and Biological Evaluation of 2‘-Methyl Taxoids Derived from Baccatin III and 14β-OH-Baccatin III 1,14-Carbonate

Battaglia, Arturo, Bernacki, Ralph J., Bertucci, Carlo, Bombardelli, Ezio, Cimitan, Samanta, Ferlini, Cristiano, Fontana, Gabriele, Guerrini, Andrea, Riva, Antonella

Journal:

Journal of Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 99 KB

english, 2003

29

Red cell hydrolases

Ralph J. Bernacki, H. Bruce Bosmann

Journal:

Journal of Membrane Biology

Year:

1972

Language:

english

File:

PDF, 927 KB

english, 1972

30

Syntheses and Structure−Activity Relationships of the Second-Generation Antitumor Taxoids: Exceptional Activity against Drug-Resistant Cancer Cells

Ojima, Iwao, Slater, John C., Michaud, Evelyne, Kuduk, Scott D., Bounaud, Pierre-Yves, Vrignaud, Patricia, Bissery, Marie-Christine, Veith, Jean M., Pera, Paula, Bernacki, Ralph J.

Journal:

Journal of Medicinal Chemistry

Year:

1996

Language:

english

File:

PDF, 256 KB

english, 1996

31

Congenital subungual nevus

Coskey, Ralph J., Magnell, Thomas D., Bernacki, Edward G.

Journal:

Journal of the American Academy of Dermatology

Year:

1983

Language:

english

File:

PDF, 2.34 MB

english, 1983

32

Growth Of Human Urologic Tumors On Extracellular Matrix

Bulbul, Muhammad A., Pavelic, Kresimir, Slocum, Harry K., Frankfurt, Oskar S., Rustum, Youcef M., Huben, Robert P., Bernacki, Ralph J.

Journal:

The Journal of Urology

Year:

1986

Language:

english

File:

PDF, 325 KB

english, 1986

33

Fluorinated carbohydrates as potential plasma membrane modifiers. Synthesis of 4- and 6-fluoro derivatives of 2-acetamido-2-deoxy-d-hexopyranoses

Moheswar Sharma, Ralph J. Bernacki, Brajeswar Paul, Walter Korytnyk

Journal:

Carbohydrate Research

Year:

1990

Language:

english

File:

PDF, 1.33 MB

english, 1990

34

Rat-Liver-Sialidase Activity Utilizing a Tritium-Labeled Sialic-Acid Derivative of Glycoprotein Substrates : Activity in Normal and Hypothrombinemic Rats

Ralph J. Bernacki, H. Bruce Bosmann

Journal:

Year:

1973

Language:

english

File:

PDF, 1.00 MB

english, 1973

35

Antitumor properties of tetrahydrobenz(a)anthraquinone derivatives

Morreal, Charles E., Bernacki, Ralph J., Hillman, Marilyn, Atwood, Alice, Cartonia, Donna

Journal:

Journal of Medicinal Chemistry

Year:

1990

Language:

english

File:

PDF, 428 KB

english, 1990

36

Synthesis and Evaluation of Analogues of 5‘-([( Z )-4-Amino-2-butenyl]methylamino)-5‘-deoxyadenosine as Inhibitors of Tumor Cell Growth, Trypanosomal Growth, and HIV-1 Infectivity †

Marasco,, Canio J., Kramer, Debora L., Miller, John, Porter, Carl W., Bacchi, Cyrus J., Rattendi, Donna, Kucera, Louis, Iyer, Nathan, Bernacki, Ralph, Pera, Paula, Sufrin, Janice R.

Journal:

Journal of Medicinal Chemistry

Year:

2002

Language:

english

File:

PDF, 176 KB

english, 2002

37

Synthesis and Biological Activity of 6-Hydroxyguanidino-and 6-Hydroxyureidopurine And Their Ribonucleosides

Dutta, Shib P., Bernacki, Ralph J., Bloch, Alexander, Chheda, Girish B.

Journal:

Nucleosides and Nucleotides

Year:

1990

Language:

english

File:

PDF, 596 KB

english, 1990

38

Synthesis and biological activity of some 1-N-substituted 2-acetamido-2-deoxy-β-d-glycopyranosylamine derivatives and related analogs

Brajeswar Paul, Ralph J. Bernacki, Walter Korytnyk

Journal:

Carbohydrate Research

Year:

1980

Language:

english

File:

PDF, 1.32 MB

english, 1980

39

Design, synthesis and biological activity of novel C2-C3′ N-Linked macrocyclic taxoids

Iwao Ojima, Xudong Geng, Songnian Lin, Paula Pera, Ralph J Bernacki

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2002

Language:

english

File:

PDF, 148 KB

english, 2002

40

Activity of a Rat-Liver Glycoprotein: Sialyltransferase Utilizing Desialyzed Prothrombin as an Acceptor in Normal and Hypothrombinemic Animals

Ralph J. Bernacki, H. Bruce Bosmann

Journal:

Year:

1973

Language:

english

File:

PDF, 1.06 MB

english, 1973

41

ChemInform Abstract: Synthesis and Structure—Activity Relationships of New Second-Generation Taxoids.

Iwao Ojima, Tao Wang, Michael L. Miller, Songnian Lin, Christopher P. Borella, Xudong Geng, Paula Pera, Ralph J. Bernacki

Journal:

Year:

2000

File:

PDF, 28 KB

2000

42

Galactosyltransferase activity and cell growth: Uridine diphosphate (UDP)galactose inhibition of murine leukemic

Wayne D. Klohs, James R. Wilson, Milton M. Weiser, Oscar Frankfurt, Ralph J. Bernacki

Journal:

Journal of Cellular Physiology

Year:

1984

Language:

english

File:

PDF, 582 KB

english, 1984

43

Synthesis, molecular modeling, and evaluation of nonphenolic indole analogs of mycophenolic acid

Moustafa E El-Araby, Ralph J Bernacki, Gergely M Makara, Paula J Pera, Wayne K Anderson

Journal:

Bioorganic & Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 447 KB

english, 2004

44

Design and synthesis of de novo cytotoxic alkaloids through mimicking taxoid skeleton

Xudong Geng, Raphaël Geney, Paula Pera, Ralph J. Bernacki, Iwao Ojima

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 308 KB

english, 2004

45

Synthesis and biological activity of novel 3′-trifluoromethyl taxoids

Iwao Ojima, John C. Slater, Paula Pera, Jean M. Veith, Ahmed Abouabdellah, Jean-Pierre Bégué, Ralph J. Bernacki

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 348 KB

english, 1997

46

Inhibition of human HT-29 colon carcinoma cell adhesion by a 4-fluoro-glucosamine analogue

Barbara Woynarowska, Charles J. Dimitroff, Moshewar Sharma, Khushi L. Matta, Ralph J. Bernacki

Journal:

Glycoconjugate Journal

Year:

1996

Language:

english

File:

PDF, 1.33 MB

english, 1996

47

Cell SurfaceN-Acetylneuraminic Acid α2,3-Galactoside-Dependent Intercellular Adhesion of Human Colon Cancer Cells

Charles J. Dimitroff, P. Pera, Fabio Dall'Olio, Khushi L. Matta, E.V. Chandrasekaran, Joseph T.Y. Lau, Ralph J. Bernacki

Journal:

Biochemical and Biophysical Research Communications

Year:

1999

Language:

english

File:

PDF, 80 KB

english, 1999

48

In vitrodegradation of extracellular matrix by human ovarian carcinoma cells

Michael J. Niedbala, Kent Crickard, Ralph J. Bernacki

Journal:

Clinical and Experimental Metastasis

Year:

1987

Language:

english

File:

PDF, 1.38 MB

english, 1987

49

The 4′-O-benzylated doxorubicin analog WP744 overcomes resistance mediated by P-glycoprotein, multidrug resistance protein and breast cancer resistance protein in cell lines and acute myeloid leukemia cells

Tracy A. Brooks, Kieran L. O’Loughlin, Hans Minderman, Brian N. Bundy, Laurie A. Ford, Michael R. Vredenburg, Ralph J. Bernacki, Waldemar Priebe, Maria R. Baer

Journal:

Investigational New Drugs

Year:

2007

Language:

english

File:

PDF, 300 KB

english, 2007

50

Cancer Metastasis: A Search for Therapeutic Inhibition

Dimitroff, Charles J., Sharma, Amamath, Bernacki, Ralph J.

Journal:

Cancer Investigation

Year:

1998

Language:

english

File:

PDF, 1.25 MB

english, 1998

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